Wednesday, September 12, 2012

Jon Cohen of Science magazine to receive Victor Cohn Medical Science Reporting Prize

Jon Cohen of Science magazine to receive Victor Cohn Medical Science Reporting Prize [ Back to EurekAlert! ] Public release date: 12-Sep-2012
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Contact: Ben Patrusky
bpatrusky@casw.org
212-254-8685
CASW/Council for the Advancement of Science Writing

Jon Cohen, a contributing correspondent for Science magazine, has been named winner of the 2012 Victor Cohn Prize for Excellence in Medical Science Reporting. The award is made in recognition of his exemplary coverage of a broad range of biomedical topics, but most notably his distinguished and persistent chronicling of the global HIV/AIDS epidemic.

The Victor Cohn prize, for a body of work published or broadcast within the last five years, is administered by the Council for the Advancement of Science Writing, Inc. (CASW), a not-for-profit organization of journalists and scientists committed to improving the quality of science news and information reaching the public.

Cohen will receive the $3,000 check and a certificate in Raleigh, North Carolina, on Saturday, October 27, at an awards ceremony to be held in conjunction with ScienceWriters2012, a joint meeting of CASW and the National Association of Science Writers (NASW).

The Cohn Prize judges lauded Cohen for his "exceptional resourcefulness, his unrelenting enterprise, his brilliant marshaling of facts and his superb story-telling skills," in articles dealing with such diverse issues as chronic fatigue syndrome, the H5N1 avian influenza pandemic, primate medical research, vaccines and immunology, emerging infectious diseases and biodefense.

They were particularly impressed by the in-depth packages of stories Cohen published in Science in advance of the major international biennial HIV/AIDS meetings. Each set covered a different corner of the globe. In the most recent package, "The Many States of HIV in America," in the July 12, 2012 issue, Cohen described, in a series of illuminating vignettes, efforts underway to better understand and stem the spread of HIV, the AIDS-causing virus, in 10 cities across the United States. Earlier packages examined the daunting challenges faced in Eastern Europe, in Latin America and the Caribbean and, before that, in Asia and Africa,

The prize committee unanimously and readily agreed with the assessment rendered by Colin Norman, news editor of Science, who, in his nominating letter, wrote: "Jon's reporting on the AIDS epidemic consistently breaks new ground.Each package highlights Jon's great strengths as a reporter: He gets into the field and talks to everybody, from top researchers and government officials to sex workers, injecting drug users, non-governmental groups, men who have sex with men, patients, law enforcement and advocates. He is meticulous in his reporting and his writing is vivid and compelling."

Cohen began writing for Science in 1990, first as a staff writer and since 1998 as a contributing correspondent. His freelance work also has appeared in many popular outlets including the New Yorker, Atlantic Monthly, the New York Times Magazine, Washington Post, Smithsonian, and Discover. Author of three books, Cohen earned his B. A. from the University of California, San Diego. From 1986 until he joined Science, he was senior editor at the City Paper in Washington, D. C. Cohen lives in Cardiff-by-the Sea, California, with his wife, TV producer Shannon Bradley and their three children.

This year's entries were judged by CASW president Cristine Russell, a freelance writer and senior fellow at Harvard's Kennedy School of Government; Joann Rogers, a freelance writer and faculty scholar at the Johns Hopkins Berman Institute of Bioethics; and Ben Patrusky, CASW's executive director.

This year marks the 13th presentation of the Victor Cohn Prize for Excellence in Medical Science Reporting. The inaugural award in 2000 was shared by Laurie Garrett of Newsday and Lawrence K. Altman of The New York Times. Subsequent recipients, in addition to Cohen, were Jon Palfreman, a public television documentarian; Shannon Brownlee, a noted magazine writer and book author; Michelle Trudeau of NPR; Rick Weiss of the Washington Post; Jerome Groopman of The New Yorker; Geeta Anand of The Wall Street Journal; Joe Palca of NPR; Denise Grady of The New York Times; Marilynn Marchionne of the Associated Press; and Ron Winslow, of The Wall Street Journal.

The award honors the late Washington Post medical writer and health columnist Victor Cohn, who distinguished himself by the clarity and effectiveness of his reporting during a 50-year career. He was a co-founder in 1959 of CASW.

###

To read more about Jon Cohen, visit www.joncohen.org
To learn more about CASW, visit www.casw.org
To learn more about ScienceWriters 12, visit www.sciencewriters2012.org


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Jon Cohen of Science magazine to receive Victor Cohn Medical Science Reporting Prize [ Back to EurekAlert! ] Public release date: 12-Sep-2012
[ | E-mail | Share Share ]

Contact: Ben Patrusky
bpatrusky@casw.org
212-254-8685
CASW/Council for the Advancement of Science Writing

Jon Cohen, a contributing correspondent for Science magazine, has been named winner of the 2012 Victor Cohn Prize for Excellence in Medical Science Reporting. The award is made in recognition of his exemplary coverage of a broad range of biomedical topics, but most notably his distinguished and persistent chronicling of the global HIV/AIDS epidemic.

The Victor Cohn prize, for a body of work published or broadcast within the last five years, is administered by the Council for the Advancement of Science Writing, Inc. (CASW), a not-for-profit organization of journalists and scientists committed to improving the quality of science news and information reaching the public.

Cohen will receive the $3,000 check and a certificate in Raleigh, North Carolina, on Saturday, October 27, at an awards ceremony to be held in conjunction with ScienceWriters2012, a joint meeting of CASW and the National Association of Science Writers (NASW).

The Cohn Prize judges lauded Cohen for his "exceptional resourcefulness, his unrelenting enterprise, his brilliant marshaling of facts and his superb story-telling skills," in articles dealing with such diverse issues as chronic fatigue syndrome, the H5N1 avian influenza pandemic, primate medical research, vaccines and immunology, emerging infectious diseases and biodefense.

They were particularly impressed by the in-depth packages of stories Cohen published in Science in advance of the major international biennial HIV/AIDS meetings. Each set covered a different corner of the globe. In the most recent package, "The Many States of HIV in America," in the July 12, 2012 issue, Cohen described, in a series of illuminating vignettes, efforts underway to better understand and stem the spread of HIV, the AIDS-causing virus, in 10 cities across the United States. Earlier packages examined the daunting challenges faced in Eastern Europe, in Latin America and the Caribbean and, before that, in Asia and Africa,

The prize committee unanimously and readily agreed with the assessment rendered by Colin Norman, news editor of Science, who, in his nominating letter, wrote: "Jon's reporting on the AIDS epidemic consistently breaks new ground.Each package highlights Jon's great strengths as a reporter: He gets into the field and talks to everybody, from top researchers and government officials to sex workers, injecting drug users, non-governmental groups, men who have sex with men, patients, law enforcement and advocates. He is meticulous in his reporting and his writing is vivid and compelling."

Cohen began writing for Science in 1990, first as a staff writer and since 1998 as a contributing correspondent. His freelance work also has appeared in many popular outlets including the New Yorker, Atlantic Monthly, the New York Times Magazine, Washington Post, Smithsonian, and Discover. Author of three books, Cohen earned his B. A. from the University of California, San Diego. From 1986 until he joined Science, he was senior editor at the City Paper in Washington, D. C. Cohen lives in Cardiff-by-the Sea, California, with his wife, TV producer Shannon Bradley and their three children.

This year's entries were judged by CASW president Cristine Russell, a freelance writer and senior fellow at Harvard's Kennedy School of Government; Joann Rogers, a freelance writer and faculty scholar at the Johns Hopkins Berman Institute of Bioethics; and Ben Patrusky, CASW's executive director.

This year marks the 13th presentation of the Victor Cohn Prize for Excellence in Medical Science Reporting. The inaugural award in 2000 was shared by Laurie Garrett of Newsday and Lawrence K. Altman of The New York Times. Subsequent recipients, in addition to Cohen, were Jon Palfreman, a public television documentarian; Shannon Brownlee, a noted magazine writer and book author; Michelle Trudeau of NPR; Rick Weiss of the Washington Post; Jerome Groopman of The New Yorker; Geeta Anand of The Wall Street Journal; Joe Palca of NPR; Denise Grady of The New York Times; Marilynn Marchionne of the Associated Press; and Ron Winslow, of The Wall Street Journal.

The award honors the late Washington Post medical writer and health columnist Victor Cohn, who distinguished himself by the clarity and effectiveness of his reporting during a 50-year career. He was a co-founder in 1959 of CASW.

###

To read more about Jon Cohen, visit www.joncohen.org
To learn more about CASW, visit www.casw.org
To learn more about ScienceWriters 12, visit www.sciencewriters2012.org


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-09/cfta-jco091112.php

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Roadside attracted to Sarah Polley's 'Stories We Tell'

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Tuesday, September 11, 2012

Blakeley Shea Jones and Tony Pieper: Engaged!


They may not have walked away with any money, but Blakeley Shea Jones and Tony Pieper got engaged last night on the Bachelor Pad season finale.

Before Nick Peterson shocked the world and screwed over Rachel Trueheart en route to $250,000, single father Tony found himself $100,000 lighter.

He popped the question to Blakeley with a ring by Hollywood fave Neil Lane.

Blakeley Shea Jones PhotoTony Pieper Photo

"It is a gorgeous ring," a diamond expert says of the 3.5-carat rock. "It's very substantial. The main stone is a square cut, with a pave border and a double pave band."

One worth an estimated hundred grand, according to reports.

About a week before the Bachelor Pad finale taped, "Tony was very quietly flown out to LA ... He met with Neil so he could pick the ring out personally."

His efforts certainly paid off, as Blakeley Shea Jones said yes.

While neither made it far on The Bachelor or Bachelorette, the couple met at the Pad and decided to make their relationship permanent after just a few months.

Congratulations, Blakeley and Tony!

Source: http://www.thehollywoodgossip.com/2012/09/blakeley-shea-jones-and-tony-pieper-engaged/

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Wolf mange part of nature's cycle

Monday, September 10, 2012

Mange and viral diseases have a substantial, recurring impact on the health and size of reintroduced wolf packs living in Yellowstone National Park, according to ecologists.

Following the restoration of gray wolves to Yellowstone in 1996, researchers collected blood from the animals to monitor parasite-induced disease and death. They also tracked the wolves in each pack to follow their survival and allow additional data-gathering.

"Many invasive species flourish because they lack their native predators and pathogens, but in Yellowstone we restored a native predator to an ecosystem that had other canids present that were capable of sustaining a lot of infections in their absence," said Emily S. Almberg, graduate student in ecology, Penn State. "It's not terribly surprising that we were able to witness and confirm that there was a relatively short window in which the reintroduced wolves stayed disease-free."

The researchers found that within a year after the wolves were reintroduced to Yellowstone, 100 percent of the wolves tested had at least one infection, but mange did not infect wolves living in the park until 2007.

"We can look at the biology of the diseases and predict which ones will come in first," said Peter J. Hudson, Willaman Professor of Biology and director of the Huck Institutes of the Life Sciences, Penn State. "What was surprising was that so many diseases came in so fast, but those were the ones we expected to come in first. It wasn't really a sequence, they were almost there immediately. That's very interesting in itself. "

The diseases that infected the wolves quickly were all viral, including canine distemper and canine parvovirus -- both contractible through bodily secretions. Mange, however, is a skin infection, caused by scabies mites, that makes the wolves scratch and lose fur. An infected wolf can lose enough body heat in the winter to freeze to death. Mange is spread by direct contact with another mite-infected animal or by contact with the mites themselves, as they can survive away from a host for several days, depending on the temperature.

"Where did those diseases come from?" asked Hudson. "Most of them initially came from other canid species, like coyotes or foxes. Wolves are animals that disperse far and move around fast, and once the wolves were established the diseases were spread from pack to pack."

Almberg and Hudson tracked how quickly mange spread from pack to pack after the disease entered the population. The number of infected wolves in a pack did not affect the likelihood of a neighboring pack to contract mange, but distance was a factor -- for every six miles of distance between an infected pack and an uninfected pack, there was a 66 percent drop in risk for the uninfected pack. Some wolves and packs were not severely affected by mange, while other packs were decimated, the researchers report in the current issue of Philosophical Transactions of the Royal Society B.

In January 2007, Mollie's pack was the first in Yellowstone to show signs of mange infection. As of March 2011, they had recovered. The Druid pack, which had been one of the most stable and visible packs in the park, according to Almberg, started to show signs of mange in August 2009.

"It was in a very short amount of time that the majority of the animals [in Druid] became severely infected," Almberg said. "The majority of their hair was missing from their bodies and it hit them right in the middle of winter. The summer before it got really bad, we saw that many of the pups had mange."

The Druid pack was gone by the end of the winter in 2010.

The researchers note that the wolf population in Yellowstone experienced several phases -- from 1995 to 2003 the wolves experienced rapid growth, from 2003 to 2007 the number of wolves stabilized, and the most recent data from 2007 to 2010 shows a decline.

"We're down to extremely low levels of wolves right now, we're down to [similar numbers as] the early years of reintroduction," said Almberg. "So it doesn't look like it's going to be as large and as a stable a population as was maybe initially thought."

Also working on this research were Paul C. Cross, disease ecologist, Northern Rocky Mountain Science Center; Andrew P. Dobson, professor of ecology and evolutionary biology, Princeton University; and Douglas W. Smith, director, Yellowstone Wolf Project.

###

Penn State: http://live.psu.edu

Thanks to Penn State for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/123334/Wolf_mange_part_of_nature_s_cycle

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Motorola Droid RAZR M Review: The Best Non-Giant Android Phone [Lightning Review]

Android phones have been getting bigger and bigger, and that's not everyone's cup of tea. As Motorola said at unveiling of the Droid RAZR M, "Some people just want a smaller phone." Does this phone, designed to fill that niche, still deliver on performance? More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/VdvmbaV9D_o/motorola-droid-razr-m-review-the-best-non+giant-android-phone

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Monday, September 10, 2012

How breast cancer spreads

ScienceDaily (Sep. 10, 2012) ? The invasion of cancer cells into the lymph vessels that connect the breast to surrounding lymph nodes is the first step leading to the metastasis, or spread, of cancer throughout the body. Metastasis is the primary cause of breast cancer deaths. Surprisingly little is known about the control of this process and how it might be interrupted to prolong the lives of women with breast cancer.

In a study to be reported Sept. 10 in the Proceedings of the National Academy of Sciences Online Early Edition, researchers at Johns Hopkins describe their discovery of how a protein responsible for cell survival in low oxygen can trigger the spread of cancer cells into the lymphatic system in a mouse model of breast cancer.

The researchers knew that like all solid tumor cancers, breast cancer cells can grow so densely that they end up starved for oxygen. To survive, cancer cells trigger the growth of new blood vessels by activating a protein called hypoxia-inducible factor 1, or HIF-1. "We've known that increased levels of HIF-1 are associated with increased tumor vessels and with patient mortality," says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine, director of the vascular program at Hopkins' Institute for Cell Engineering and a member of the McKusick-Nathans Institute of Genetic Medicine. "Now we've found that HIF-1 activity is directly responsible for the spread of breast cancer to the lymph vessels."

Working in mice injected with human breast cancer cells, which when left undisturbed grow into tumors that spread from the breast to the lungs, Semenza's team previously found that interfering with HIF-1 in these mice reduced growth of the primary tumor and prevented metastasis through blood vessels to the lung. "So of course we wanted to see whether blocking HIF-1 could affect lymph node metastasis as well," he says.

In new experiments, they injected mice with human breast cancer cells that were genetically engineered to knock down HIF-1 protein levels and, after 24 days, examined the mouse lymph nodes to see if the human breast cancer cells had spread. They found that compared to mice whose HIF-1 levels were left undisturbed, lymph nodes with knocked-down HIF-1 contained 76 percent fewer human breast cancer cells, supporting the idea that HIF-1 is somehow involved in the spread of breast cancer to lymph nodes.

To better understand how HIF-1 triggers this to happen, Semenza's team then starved human breast cancer cells of oxygen to see which of the genes involved in the growth of lymphatic vessels might respond to HIF-1. They found that the platelet-derived growth factor B gene -- PDGF-B -- was five times more active when oxygen was lacking. A closer look at the DNA sequence around the PDGF-B gene showed regions of DNA known to be recognized and bound by the HIF-1 protein. They tested this in cells and found that, indeed, HIF-1 protein binds to the PDGF-B gene and turns it on.

The team then took a closer look at PDGF-B to find out how it works once the gene is turned on. They found that PDGF-B that is made by breast cancer cells is pumped out of the cell and stimulates the growth of lymph vessels.

Treating the mice with either digoxin, which blocks HIF-1 activity, or imatinib, a cancer drug, reduced tumor size by 78 percent and reduced lymph node metastasis by 94 percent, although the researchers emphasized that more work must be done to determine whether these drugs will be effective in treating breast cancer patients.

"We're very excited by these results, having shown for the first time that HIFs are directly involved in the lymphatic metastasis of breast cancer," says Semenza. "These results provide experimental support for breast cancer clinical trials that target HIF-1 or PDGF-B." The first study of digoxin in women with breast cancer at the Johns Hopkins Oncology Center will begin later this year.

This study was funded by grants from the American Cancer Society and the National Cancer Institute (U54-143868) and by funds from the Johns Hopkins Institute for Cell Engineering.

Authors on the paper are Luana Schito, Sergio Rey, Huafeng Zhang, Carment Chak-Lui Wong and Gregg Semenza of Johns Hopkins; Marco Tafani and Matteo Russo of Sapienza University of Rome, Rome, Italy; and Andrea Russo of Istituti Fisioterapici Ospitalieri, Rome, Italy.

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The above story is reprinted from materials provided by Johns Hopkins Medicine, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Luana Schito, Sergio Rey, Marco Tafani, Huafeng Zhang, Carmen Chak-Lui Wong, Andrea Russo, Matteo A. Russo, and Gregg L. Semenza. Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells. PNAS, September 10, 2012 DOI: 10.1073/pnas.1214019109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/UajUJbm6F1U/120910151052.htm

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Reality Check: Romney-Ryan tax reform plan (CNN)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/247312155?client_source=feed&format=rss

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